HIGH-DOSE DAPTOMYCIN AND FOSFOMYCIN TREATMENT OF A PATIENT WITH ENDOCARDITIS CAUSED BY DAPTOMYCIN-NONSUSCEPTIBLE STAPHYLOCOCCUS AUREUS: CASE REPORT

High-dose daptomycin and fosfomycin treatment of a patient with endocarditis caused by daptomycin-nonsusceptible Staphylococcus aureus: Case report

Abstract Background Emergence of daptomycin-nonsusceptible (DNS) Staphylococcus aureus is a dreadful problem in the treatment of endocarditis.Few current therapeutic agents are effective for treating infections caused by DNS S.aureus.Case presentation We describe the emergence torpedo of DNS S.aureus.in a patient with implantable cardioverter-defib

read more



HIV aspartyl peptidase inhibitors interfere with cellular proliferation, ultrastructure and macrophage infection of Leishmania amazonensis.

BACKGROUND: Leishmania is the etiologic agent of leishmanisais, a protozoan disease whose pathogenic events are not well understood.Current therapy is suboptimal due to toxicity of the available therapeutic agents and the emergence of drug resistance.Compounding these problems is the increase in the number of cases of Leishmania-HIV coinfection, du

read more

The percutaneous permeation of a combination of 0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol (octenisept®) through skin of different species in vitro

Abstract Background A water based combination of 0.1% octenidine dihydrochloride and 2% 2 - phenoxyethanol is registered in many European countries as an antiseptic solution C 500MG - PECH (octenisept®) for topical treatment with high antimicrobial activity for human use, but octenidine based products have not been registered for veterinary use ye

read more